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David Lynn M.Sc., Ph.D.,
Department of Molecular Biology and Biochemistry, IRMACS Centre, Simon Fraser University, Burnaby, Vancouver B.C., Canada. Email: dlynn AT sfu.ca
David J. Lynn Ph.D.
Publications:
Gardy J.L., Lynn D.J.*,, Brinkman F.S.L, Hancock R.E.W. (2009). Enabling a systems biology approach to immunology: focus on innate immunity Trends in Immunology 30(6), 249-62.
Downing T., Lynn D.J.,,Connell S., Lloyd A.T., Bhuiyan A.K.F.H., Silva P., Naqvi A., Sanfo R.,Sow R.S., Podisi B., Hanotte O., O.Farrelly C., Bradley D.G. (2009).Evidence of balanced diversity at the chicken interleukin 4 receptoralpha chain locus. BMC Evolutionary Biology 9(1):136.
The Bovine Genome Sequencing and Analysis Consortium (2009). The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution. Science 324(5926), 522-8.
The Bovine HapMap Consortium (2009). Genome Wide Survey of SNP Variation Uncovers the Genetic Structure of Cattle Breeds. Science 324(5926), 528-32.
Downing T., Lynn D.J.,,Connell S., Lloyd A.T., Bhuiyan A.K.F.H., Silva P., Naqvi A., Sanfo R.,Sow R.S., Podisi B., O.Farrelly C., Hanotte O., Bradley D.G. (2009).Contrasting Evolution of Diversity at Two Disease-Associated ChickenGenes. Immunogenetics 61(4), 303-14.
Lemay D.G., Lynn D.J.,,Martin W.F., Casey T.M., Kriventseva E.V., Rincon G., Barris W.,Hinrichs A.S., Molenaar A.J., Pollard K.S., Neville M.C., Maqbool N.J.,Zdobnov E.M., Medrano J.F., Tellam R., German J.B., Rijnkels M. (2009).The Bovine Lactation Genome: Insights into the Evolution of MammalianMilk. Genome Biology 10(4):R43.
Lynn D.J., Winsor G.L., Chan C., Richard N., Laird M.R., Barsky A., Gardy J.L.,Roche F.M., Chan T.H.W., Shah N., Lo R., Naseer M., Que J., Yau M., Acab M., TulpanD., Whiteside M.D., Chikatamarla A., Mah B., Munzner T., Hokamp K., HancockR.E.W., Brinkman F.S.L. (2008). InnateDB - Facilitating Systems Level Analyzesof the Mammalian Innate Immune Response. Molecular Systems Biology4:218.
Freeman A.R., Lynn D.J.*,, Murray C., Bradley D.G. (2008). Detecting the Effects of Selection at the Population Level in Bovine Immune Genes. BMC Genetics 9:62.
Lynn D.J.* , Higgs R., Lloyd A.T., Herve-Grepinet V., Nys Y., Brinkman F.S.L.,Yu P.L., Soulier A., Kaiser P., Zhang G., O'Farrelly C., LehrerR.I. (2007). Avian Beta-Defensin Nomenclature: A Community Proposed Update.Immunology Letters 110(1), 86-89.
Higgs R., Lynn D.J.,Alana I., Cahalane S., Hewage C.W., James T., Lloyd A.T., O'Farrelly C.(2007). Modification of chicken avian beta-defensin-8 at positivelyselected amino acid sites enhances specific antimicrobial activity. Immunogenetics 59(7), 573-580.
Lynn D.J.*, Bradley D.G. (2007). Discovery of alpha-Defensins in Basal Mammals. Developmental & Comparative Immunology 31(10), 963-967.
Cruz F., Bradley D.G., Lynn D.J.* (2007). Evidence of Positive Selection on the Atlantic Salmon CD3gamma-delta gene. Immunogenetics 59(3), 225-232.
Murphy A.M., Machugh D.E., Park S.D., Scraggs E., Haley C.S., Lynn D.J., Boland M.P., DohertyM.L. (2007). Linkage Mapping of the Locus for Inherited Ovine Arthrogryposis (IOA) to Sheep Chromosome 5. Mammalian Genome 18(1), 43-52.
Higgs R., Cormican P., Cahalane S., Allan B., Lloyd A.T., Meade K., James T., Lynn D.J.,Babiuk L., O'Farrelly C. (2006). Induction of a Novel Chicken Toll-likeReceptor following Salmonella enterica serovar Typhimurium Infection. Infection and Immunity 74(3), 1692-1698. PMID: 16495540 |